TRAC Rabbit Monoclonal Antibody [Clone ID: 34]

Specifications

Product Data
Clone Name	34
Applications	ELISA, FC, WB
Reactivity	Human
Host	Rabbit
Clonality	Monoclonal
Immunogen	Purified recombinant soluble TCR from the T-cell hybridoma 85.33, corresponding to V alpha 11
Specificity	This antibody binds to the T-cell receptor alpha chains. The antibody binds specifically to the recombinant and native variable domain of the α chain which comprises the T-cell receptor (TCR). The TCR is a disulfide-linked heterodimeric protein expressed on the surface of T-cells in complex with CD3 and ζ-chain molecules. The receptor functions in the recognition of MHC molecule and the subsequent activation of T-cells. The monoclonal antibody 34 recognises Vα regions of TCRs expressed in the 85.33 arthritogenic T-cell hybridoma and can be used to analyse TCR V gene expression and for immunotherapy in T cell mediated autoimmunity.
Formulation	PBS with 0.02% Proclin 300.
Concentration	lot specific
Conjugation	Unconjugated
Storage Condition	Please store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C. Avoid freeze and thaw cycles.
Gene Name	T-cell receptor alpha constant
Database Link	Entrez Gene 28755 Human UniProt ID P01848
Note	This full-length, chimeric rabbit antibody was made using the variable domain sequences of the original Mouse scFv format, for improved compatibility with existing reagents, assays and techniques.
Reference Data

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