CD55 Mouse Monoclonal Antibody [Clone ID: LU30]

Specifications

Product Data
Clone Name	LU30
Applications	ELISA, IHC, WB
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Human CD55.
Specificity	The antibody binds to CD55 with a Kd of 13 nM. The antibody binds specifically to CD55, a glycophosphatidylinositol-anchored protein which acts together with CD46 and CD59 to protect cells from complement-mediated cell lysis. The antigen recognises C4b, C3 and C3b complement components, and, by blocking their catalytic activity, inhibits the formation of the membrane attack complex. CD55 is overexpressed in many tumour cell lines, thereby inhibiting complement-mediated cell lysis and increases tumour resistance to immune attacks.
Formulation	PBS with 0.02% Proclin 300.
Concentration	lot specific
Conjugation	Unconjugated
Storage Condition	Please store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C. Avoid freeze and thaw cycles.
Gene Name	CD55 molecule (Cromer blood group)
Database Link	Entrez Gene 1604 Human UniProt ID P08174
Synonyms	CR; CROM; DAF; TC
Note	This chimeric mouse antibody was made using the variable domain sequences of the original Human format, for improved compatibility with existing reagents, assays and techniques.
Reference Data

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