CD11b (ITGAM) Mouse Monoclonal Antibody [Clone ID: 107]

Specifications

Product Data
Clone Name	107
Applications	ELISA, FC
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Wild type (WT) recombinant CD11b.
Specificity	This antibody binds to the MIDAS face of the A domain from integrin CD11b. The antibody binds specifically to integrin α-M, a protein subunit of the α-M- β-2 molecule, which is expressed on the surface of leukocytes. Integrin α-M is involved in the adhesive interaction between molecules of the innate immune system, and plays a role in the uptake of complement-coated particles. The monoclonal antibody 107 has a blocking activity by binding to the metal-ion-dependent-adhesion site, favouring a low affinity conformation of the antigen.
Formulation	PBS with 0.02% Proclin 300.
Concentration	lot specific
Conjugation	Unconjugated
Storage Condition	Please store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C. Avoid freeze and thaw cycles.
Gene Name	integrin subunit alpha M
Database Link	Entrez Gene 3684 Human UniProt ID P11215
Synonyms	CD11B; CR3A; MAC-1; MAC1A; MGC117044; MO1A; SLEB6
Reference Data

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