MCK10 (DDR1) Rabbit Monoclonal Antibody [Clone ID: 3000]

Specifications

Product Data
Clone Name	3000
Applications	Bl, ELISA, WB
Reactivity	Human
Host	Rabbit
Clonality	Monoclonal
Immunogen	Recombinant human DDR1 extracellular domain.
Specificity	This antibody binds specifically to the extracellular domain of human DDR1. This antibody binds to human Discoidin Domain Receptor 1, a receptor tyrosine kinase that functions as cell surface receptor for fibrillar collagen and regulates the attachemnt of the cell to the extracellular matrix. This receptor is required for blastocyst implantation during pregnancy, mammary gland differentiation as well as lactation. It promotes smooth muscle cell migration as well as tumour cell invasion. The antibody acts as an antagonist.
Formulation	PBS with 0.02% Proclin 300.
Concentration	lot specific
Conjugation	Unconjugated
Storage Condition	Please store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C. Avoid freeze and thaw cycles.
Gene Name	discoidin domain receptor tyrosine kinase 1
Database Link	Entrez Gene 780 Human UniProt ID Q08345
Synonyms	CAK; CD167; DDR; EDDR1; HGK2; MCK-10; MCK10; NEP; NTRK4; OTTHUMP00000029344; OTTHUMP00000029345; OTTHUMP00000029346; OTTHUMP00000029347; PTK3; PTK3A; RTK6; TRKE
Note	This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG2a format, for improved compatibility with existing reagents, assays and techniques.
Reference Data

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