Cd28 Rabbit Monoclonal Antibody [Clone ID: D665]

Specifications

Product Data
Clone Name	D665
Applications	FC, IHC
Reactivity	Mouse
Host	Rabbit
Clonality	Monoclonal
Immunogen	The original D665 antibody was generated by immunizing mice alternately with A20 cells expressing mCD28 i.p. and with recombinant mCD28Ig s.c.
Specificity	This antibody binds to the laterally exposed C′D loop of CD28 and induces T cell proliferation without TCR ligation. This antibody binds to mouse CD28. The original mouse IgG1 version was shown to trigger T-cell proliferation in vitro and in vivo in a TCR-independent manner and is a superagonistic antibody. This antibody does not compete with E18 (Ab00286).
Formulation	PBS with 0.02% Proclin 300.
Concentration	lot specific
Conjugation	Unconjugated
Storage Condition	Please store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C. Avoid freeze and thaw cycles.
Gene Name	CD28 antigen
Database Link	Entrez Gene 12487 Mouse UniProt ID P31041
Synonyms	MGC138290; Tp44
Note	This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.
Reference Data

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