CD4 Mouse Monoclonal Antibody [Clone ID: MT310]

Specifications

Product Data
Clone Name	MT310
Applications	FC, IF, IHC, IP, WB
Reactivity	Human, Monkey
Host	Mouse
Clonality	Monoclonal
Specificity	mt310 binds to the extracellular domain D1 of CD4 – the same site as the HIV-1 gp120-binding site mt310 can inhibit gp120 binding to CD4, which blocks HIV infectivity of CD4+ T lymphocytes, as well as the binding of MHCII, which results in the block of T-cell activation, possibly leading to the induction of anergy. Antibody binding to CD4 additionally causes the induction of GM-CSF, TNF-α (only after 20 h) and IL-10.
Formulation	PBS with 0.02% Proclin 300.
Concentration	lot specific
Conjugation	Unconjugated
Storage Condition	Please store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C. Avoid freeze and thaw cycles.
Gene Name	CD4 molecule
Database Link	Entrez Gene 920 Human UniProt ID P01730
Synonyms	CD4mut
Reference Data

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