TXNRD1 Rabbit Monoclonal Antibody [Clone ID: R01-8I4]

Specifications

Product Data
Clone Name	R01-8I4
Applications	IF, IHC, IP, WB
Recommend Dilution	WB: 1/1000-1/5000 IHC: 1/20 ICC/IF: 1/20-1/100 IP: 1/20
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Monoclonal
Immunogen	Recombinant protein of human TXNRD1
Formulation	50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Concentration	lot specific
Purification	Affinity Purified
Conjugation	Unconjugated
Storage Condition	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Predicted Protein Size	Calculated MW: 67 kDa; Observed MW: 55 kDa
Gene Name	thioredoxin reductase 1
Database Link	Entrez Gene 7296 Human UniProt ID Q16881
Background	Swiss-Prot Acc.Q16881.Isoform 1 may possess glutaredoxin activity as well as thioredoxin reductase activity and induces actin and tubulin polymerization, leading to formation of cell membrane protrusions. Isoform 4 enhances the transcriptional activity of estrogen receptors alpha and beta while isoform 5 enhances the transcriptional activity of the beta receptor only. Isoform 5 also mediates cell death induced by a combination of interferon-beta and retinoic acid.
Synonyms	GRIM-12; KDRF; MGC9145; oxidoreductase; TR; TR1; TRXR1; TXNR
Reference Data

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