SCD1 (SCD) Rabbit Monoclonal Antibody [Clone ID: R04-2K1]

Specifications

Product Data
Clone Name	R04-2K1
Applications	IF, IHC, IP, WB
Recommend Dilution	WB: 1/1000 IHC: 1/200 ICC/IF: 1/20-1/100 IP: 1/20
Reactivity	Human
Host	Rabbit
Clonality	Monoclonal
Immunogen	Recombinant protein of human SCD1
Formulation	50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Concentration	lot specific
Purification	Affinity Purified
Conjugation	Unconjugated
Storage Condition	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Predicted Protein Size	Calculated MW: 42 kDa; Observed MW: 37 kDa
Gene Name	stearoyl-CoA desaturase
Database Link	Entrez Gene 6319 Human UniProt ID O00767
Background	Swiss-Prot Acc.O00767.Stearyl-CoA desaturase that utilizes O2 and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates (PubMed:15907797, PubMed:18765284). Catalyzes the insertion of a cis double bond at the delta-9 position into fatty acyl-CoA substrates including palmitoyl-CoA and stearoyl-CoA (PubMed:15907797, PubMed:18765284). Gives rise to a mixture of 16:1 and 18:1 unsaturated fatty acids (PubMed:15610069). Plays an important role in lipid biosynthesis. Plays an important role in regulating the expression of genes that are involved in lipogenesis and in regulating mitochondrial fatty acid oxidation . Plays an important role in body energy homeostasis . Contributes to the biosynthesis of membrane phospholipids, cholesterol esters and triglycerides .
Synonyms	Delta(9)-desaturase; delta-9-desaturase; FADS5; MSTP008; SCD1; SCDOS
Reference Data

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