PSMB8 Mouse Monoclonal Antibody [Clone ID: 3G3-C1-E2]

CAT#: TA385067

Proteasome beta 8 (3G3) Mouse monoclonal Antibody

Size: 20 ul 100 ul



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CNY 1,999.00

CNY 3,280.00


货期*
2周

规格
    • 100 ul

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beta Actin Mouse Monoclonal Antibody, Clone OTI1, Loading Control
    • 30 ul

CNY 300.00
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Specifications

Product Data
Clone Name 3G3-C1-E2
Applications IF, IHC, WB
Recommend Dilution WB: 1/500-1/2000
IHC: 1/200-1/1000
ICC: 1/200-1/1000
Reactivity Human, Rat
Host Mouse
Clonality Monoclonal
Immunogen Purified recombinant fragment of human PSMB8 expressed in E. Coli.
Formulation Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.03% Proclin 300, pH 7.3.
Concentration lot specific
Purification Ascitic Fluid
Conjugation Unconjugated
Storage Condition Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Predicted Protein Size 30kDa
Gene Name proteasome subunit beta 8
Background Swiss-Prot Acc.P28062.The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. This gene is located in the class II region of the MHC (major histocompatibility complex). Expression of this gene is induced by gamma interferon and this gene product replaces catalytic subunit 3 (proteasome beta 5 subunit) in the immunoproteasome. Proteolytic processing is required to generate a mature subunit. Two alternative transcripts encoding two isoforms have been identified; both isoforms are processed to yield the same mature subunit.
Synonyms beta5i; D6S216; D6S216E; LMP7; MGC1491; PSMB5i; RING10; Y2
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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