PAK2 Mouse Monoclonal Antibody [Clone ID: 7H3-E2-F5]

Specifications

Product Data
Clone Name	7H3-E2-F5
Applications	IF, IHC, WB
Recommend Dilution	WB: 1/500-1/2000 IHC: 1/200-1/1000 ICC: 1/200-1/1000
Reactivity	Human, Monkey
Host	Mouse
Clonality	Monoclonal
Immunogen	Purified recombinant fragment of PAK2 expressed in E. Coli.
Formulation	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.03% Proclin 300, pH 7.3.
Concentration	lot specific
Purification	Ascitic Fluid
Conjugation	Unconjugated
Storage Condition	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Predicted Protein Size	61kDa
Gene Name	p21 (RAC1) activated kinase 2
Database Link	Entrez Gene 5062 Human UniProt ID Q13177
Background	Swiss-Prot Acc.Q13177.PAK2, also known as P21 (CDKN1A)-activated kinase 2. The p21 activated kinases (PAK) are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. The PAK proteins are a family of serine/threonine kinases that serve as targets for the small GTP binding proteins, CDC42 and RAC1, and have been implicated in a wide range of biological activities. PAK2 is activated by proteolytic cleavage during caspase-mediated apoptosis, and may play a role in regulating the apoptotic events in the dying cell. PAK2 has been shown to interact with SH3KBP1, CDC42 and Abl gene.
Synonyms	Gamma-PAK; p58; PAK-2; PAK65; PAKgamma
Reference Data

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