LPP Mouse Monoclonal Antibody [Clone ID: 6F6-C1-B6]

Specifications

Product Data
Clone Name	6F6-C1-B6
Applications	IF, IHC, IP, WB
Recommend Dilution	WB: 1/500-1/2000 IHC: 1/200-1/1000 ICC: 1/200-1/1000 IP: 1/20
Reactivity	Human, Mouse, Rat, Monkey, Hamster
Host	Mouse
Clonality	Monoclonal
Immunogen	Purified recombinant fragment of human LPP expressed in E. Coli.
Formulation	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.03% Proclin 300, pH 7.3.
Concentration	lot specific
Purification	Ascitic Fluid
Conjugation	Unconjugated
Storage Condition	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Predicted Protein Size	66kDa
Gene Name	LIM domain containing preferred translocation partner in lipoma
Database Link	Entrez Gene 4026 Human UniProt ID Q93052
Background	Swiss-Prot Acc.Q93052.LIM domain containing preferred translocation partner in lipoma. The Zyxin family of proteins contains five members, Ajuba, LIMD1, LPP,TRIP6 and Zyxin. LPP (LIM-containing lipoma-preferred partner), a LIM domain-containing scaffolding protein contains three LIM domains at its carboxyterminus, which are preceded by a proline-rich pre-LIM region containing a number of protein interaction domains. LPP, an 80 kDa protein, localizes to sites of cell adhesion, such as focal adhesions and cell-cell contacts,and shuttles to the nucleus where it has transcriptional activation capacity.The human LPP gene maps to chromosomal location 3q28, and preferentiallytranslocates to the HMGIC gene in a subclass of human benign mesenchymal tumors known as lipomas.
Synonyms	LPP
Reference Data

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