Cytokeratin 17 (KRT17) Mouse Monoclonal Antibody [Clone ID: 8C6-4H2-5C1]

Specifications

Product Data
Clone Name	8C6-4H2-5C1
Applications	IF, IHC, IP, WB
Recommend Dilution	WB: 1/1000 IP: 1/200 IF: 1/200 IHC: 1/50-300
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Synthetic Peptide of CK17
Formulation	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.03% Proclin 300, pH 7.3.
Concentration	lot specific
Purification	Affinity Purified
Conjugation	Unconjugated
Storage Condition	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Predicted Protein Size	Observed MW (kDa):48
Gene Name	keratin 17
Database Link	Entrez Gene 3872 Human UniProt ID Q04695
Background	Swiss-Prot Acc.Q04695.Type I keratin involved in the formation and maintenance of various skin appendages, specifically in determining shape and orientation of hair . Required for the correct growth of hair follicles, in particular for the persistence of the anagen (growth) state . Modulates the function of TNF-alpha in the specific context of hair cycling. Regulates protein synthesis and epithelial cell growth through binding to the adapter protein SFN and by stimulating Akt/mTOR pathway . Involved in tissue repair. May be a marker of basal cell differentiation in complex epithelia and therefore indicative of a certain type of epithelial
Synonyms	39.1; CK-17; Cytokeratin-17; K17; Keratin-17; PC; PC2; PCHC1
Reference Data

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