CD41 (ITGA2B) Mouse Monoclonal Antibody [Clone ID: 9G4-3F4-10B8]

Specifications

Product Data
Clone Name	9G4-3F4-10B8
Applications	IHC
Recommend Dilution	IHC: 1/100
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Synthetic Peptide of CD41
Formulation	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.03% Proclin 300, pH 7.3.
Concentration	lot specific
Purification	Affinity Purified
Conjugation	Unconjugated
Storage Condition	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Gene Name	integrin subunit alpha 2b
Database Link	Entrez Gene 3674 Human UniProt ID P08514
Background	Swiss-Prot Acc.P08514.Integrin alpha-IIb/beta-3 is a receptor for fibronectin, fibrinogen, plasminogen, prothrombin, thrombospondin and vitronectin. It recognizes the sequence R-G-D in a wide array of ligands. It recognizes the sequence H-H-L-G-G-G-A-K-Q-A-G-D-V in fibrinogen gamma chain. Following activation integrin alpha-IIb/beta-3 brings about platelet/platelet interaction through binding of soluble fibrinogen. This step leads to rapid platelet aggregation which physically plugs ruptured endothelial cell surface.RegionsFeature keyPosition(s)Description
Synonyms	CD41; CD41B; GP2B; GPIIb; GTA; HPA3; ITGAB
Reference Data

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