hnRNP K (HNRNPK) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IF, IHC, IP, WB
Recommend Dilution	WB: 1/1000 IHC: 1/50-1/200 ICC/IF: 1/50-1/200 IP: 1/20
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	A synthesized peptide derived from human hnRNP K
Formulation	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration	lot specific
Purification	Affinity Chromatography
Conjugation	Unconjugated
Storage Condition	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Predicted Protein Size	60kDa
Gene Name	heterogeneous nuclear ribonucleoprotein K
Database Link	Entrez Gene 3190 Human UniProt ID P61978
Background	Swiss-Prot Acc.P61978.Facilitate pre-mRNA processing and transport of mRNA from the nucleus to cytoplasm. hnRNP K contains three unique structural motifs termed KH domains that bind poly(C) DNA and RNA sequences. Intricate architecture enables hnRNP K to facilitate mRNA biosynthesis, transcriptional regulation, and signal transduction. Research studies have shown that cytoplasmic hnRNP K expression is increased in oral squamous cell carcinoma and pancreatic cancer, and may be a potential prognostic factor.
Synonyms	CSBP; FLJ41122; HNRPK; OTTHUMP00000021554; OTTHUMP00000021558; TUNP
Reference Data

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