HB EGF (HBEGF) Rabbit Monoclonal Antibody [Clone ID: R08-9C2]

Specifications

Product Data
Clone Name	R08-9C2
Applications	WB
Recommend Dilution	WB: 1/2000-1/10000
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Monoclonal
Immunogen	A synthetic peptide of human HBEGF
Formulation	50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Concentration	lot specific
Purification	Affinity Purified
Conjugation	Unconjugated
Storage Condition	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Predicted Protein Size	Calculated MW: 23 kDa; Observed MW: 23 kDa
Gene Name	heparin binding EGF like growth factor
Database Link	Entrez Gene 1839 Human UniProt ID Q99075
Background	Swiss-Prot Acc.Q99075.Growth factor that mediates its effects via EGFR, ERBB2 and ERBB4. Required for normal cardiac valve formation and normal heart function. Promotes smooth muscle cell proliferation. May be involved in macrophage-mediated cellular proliferation. It is mitogenic for fibroblasts, but not endothelial cells. It is able to bind EGF receptor/EGFR with higher affinity than EGF itself and is a far more potent mitogen for smooth muscle cells than EGF. Also acts as a diphtheria toxin receptor.SitesFeature keyPosition(s)Description
Synonyms	DTR; DTS; DTSF; HEGFL
Reference Data

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