FBP1 Rabbit Monoclonal Antibody [Clone ID: R04-1D6]

Specifications

Product Data
Clone Name	R04-1D6
Applications	IHC, WB
Recommend Dilution	WB: 1/1000-1/5000 IHC: 1/20-1/50
Reactivity	Human, Rat
Host	Rabbit
Clonality	Monoclonal
Immunogen	A synthetic peptide of human FBP1
Formulation	50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Concentration	lot specific
Purification	Affinity Purified
Conjugation	Unconjugated
Storage Condition	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Predicted Protein Size	Calculated MW: 37 kDa; Observed MW: 37 kDa
Gene Name	fructose-bisphosphatase 1
Database Link	Entrez Gene 2203 Human UniProt ID P09467
Background	Swiss-Prot Acc.P09467.Catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate in the presence of divalent cations, acting as a rate-limiting enzyme in gluconeogenesis. Plays a role in regulating glucose sensing and insulin secretion of pancreatic beta-cells. Appears to modulate glycerol gluconeogenesis in liver. Important regulator of appetite and adiposity; increased expression of the protein in liver after nutrient excess increases circulating satiety hormones and reduces appetite-stimulating neuropeptides and thus seems to provide a feedback mechanism to limit weight gain.
Synonyms	FBP
Reference Data

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