Fadd Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	FC, IHC, WB
Recommend Dilution	WB: 1/500-1/2000 IHC: 1/50-1/200 FC: 1/50
Reactivity	Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	A synthesized peptide derived from human FADD
Formulation	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration	lot specific
Purification	Affinity Chromatography
Conjugation	Unconjugated
Storage Condition	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Predicted Protein Size	28kDa
Gene Name	Fas (TNFRSF6)-associated via death domain
Database Link	Entrez Gene 14082 Mouse UniProt ID Q61160
Background	Swiss-Prot Acc.Q61160.Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis.
Synonyms	GIG3; MGC8528; MORT1
Reference Data

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.