DGAT1 Rabbit Monoclonal Antibody [Clone ID: R02-4G6]

Specifications

Product Data
Clone Name	R02-4G6
Applications	IHC, IP, WB
Recommend Dilution	WB: 1/2000-1/10000 IHC: 1/20 IP: 1/20
Reactivity	Human
Host	Rabbit
Clonality	Monoclonal
Immunogen	Recombinant protein of human DGAT1
Formulation	50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Concentration	lot specific
Purification	Affinity Purified
Conjugation	Unconjugated
Storage Condition	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Predicted Protein Size	Calculated MW: 55 kDa; Observed MW: 55 kDa
Gene Name	diacylglycerol O-acyltransferase 1
Database Link	Entrez Gene 8694 Human UniProt ID O75907
Background	Swiss-Prot Acc.O75907.Catalyzes the terminal and only committed step in triacylglycerol synthesis by using diacylglycerol and fatty acyl CoA as substrates. In contrast to DGAT2 it is not essential for survival. May be involved in VLDL (very low density lipoprotein) assembly. In liver, plays a role in esterifying exogenous fatty acids to glycerol. Functions as the major acyl-CoA retinol acyltransferase (ARAT) in the skin, where it acts to maintain retinoid homeostasis and prevent retinoid toxicity leading to skin and hair disorders.
Synonyms	AGRP1; ARGP1; DGAT
Reference Data

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