IKK alpha (CHUK) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	ELISA, IHC, WB
Recommend Dilution	WB: 1/500-1/2000 IHC: 1/100-1/300 ELISA: 1/20000
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	The antiserum was produced against synthesized peptide derived from human IKK-alpha/beta. AA range:141-190
Formulation	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Concentration	lot specific
Purification	Affinity Chromatography
Conjugation	Unconjugated
Storage Condition	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Predicted Protein Size	Observed MW (kDa):85
Gene Name	conserved helix-loop-helix ubiquitous kinase
Database Link	Entrez Gene 1147 Human UniProt ID O15111
Background	Swiss-Prot Acc.O15111/O14920.CHUK encodes a member of the serine/threonine protein kinase family. Inhibitor of nuclear factor kappa-B kinase subunit alpha, a component of a cytokine-activated protein complex that is an inhibitor of the essential transcription factor NF-kappa-B complex, phosphorylates sites that trigger the degradation of the inhibitor via the ubiquination pathway, thereby activating the transcription factor.
Synonyms	IkBKA; IKK-A; IKK-alpha; IKK1; IKKA; NFKBIKA; TCF16
Reference Data

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