ATG4C Rabbit Monoclonal Antibody [Clone ID: R08-8G9]

CAT#: TA383767S

ATG4C Rabbit monoclonal Antibody

Size: 20 ul 100 ul



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CNY 800.00


货期*
2周

规格
    • 20 ul

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Specifications

Product Data
Clone Name R08-8G9
Applications IHC, WB
Recommend Dilution WB: 1/1000
IHC: 1/50
Reactivity Human
Host Rabbit
Clonality Monoclonal
Immunogen Recombinant protein of human ATG4C
Formulation 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Concentration lot specific
Purification Affinity Purified
Conjugation Unconjugated
Storage Condition Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Predicted Protein Size Calculated MW: 53 kDa; Observed MW: 53 kDa
Gene Name autophagy related 4C cysteine peptidase
Background Swiss-Prot Acc.Q96DT6.Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. Is not essential for autophagy development under normal conditions but is required for a proper autophagic response under stressful conditions such as prolonged starvation . Cleaves the C-terminal amino acid of ATG8 family proteins MAP1LC3 and GABARAPL2, to reveal a C-terminal glycine. Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes, which is necessary for autophagy. Has also an activity of delipidating enzyme for the PE-conjugated forms.
Synonyms APG4-C; APG4C; AUTL1; AUTL3; autophagin-3; FLJ14867
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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