STAT1 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, IP, WB
Recommend Dilution	WB,1:500 - 1:2000 IHC,1:50 - 1:100 IP,1:50 - 1:100
Reactivity	Human, Mouse, Rat
Modifications	Phospho S727
Host	Rabbit
Clonality	Polyclonal
Immunogen	A synthetic phosphorylated peptide around S727 of human STAT1 (NP_009330.1).
Formulation	PBS with 0.05% proclin300,50% glycerol,pH7.3.
Concentration	lot specific
Purification	Affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20℃. Avoid freeze / thaw cycles.
Predicted Protein Size	83kDa/87kDa
Gene Name	signal transducer and activator of transcription 1
Database Link	Entrez Gene 6772 Human UniProt ID P42224
Background	The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein can be activated by various ligands including interferon-alpha, interferon-gamma, EGF, PDGF and IL6. This protein mediates the expression of a variety of genes, which is thought to be important for cell viability in response to different cell stimuli and pathogens. Two alternatively spliced transcript variants encoding distinct isoforms have been described.
Synonyms	DKFZp686B04100; ISGF-3; OTTHUMP00000205845; STAT91
Reference Data

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