RUNX1 Rabbit Polyclonal Antibody
CAT#: TA381191
RUNX1 Rabbit polyclonal Antibody
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货期*
2周
规格
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Specifications
Product Data | |
Applications | WB |
Recommend Dilution | WB,1:500 - 1:2000 |
Reactivity | Human, Mouse, Rat |
Modifications | Unmodified |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 221-480 of human RUNX1 (NP_001745.2). |
Formulation | PBS with 0.09% Sodium azide,50% glycerol,pH7.3. |
Concentration | lot specific |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage Condition | Store at -20℃. Avoid freeze / thaw cycles. |
Predicted Protein Size | 20-28kDa/37kDa/48-51kDa |
Gene Name | runt related transcription factor 1 |
Database Link | |
Background | Core binding factor (CBF) is a heterodimeric transcription factor that binds to the core element of many enhancers and promoters. The protein encoded by this gene represents the alpha subunit of CBF and is thought to be involved in the development of normal hematopoiesis. Chromosomal translocations involving this gene are well-documented and have been associated with several types of leukemia. Three transcript variants encoding different isoforms have been found for this gene. |
Synonyms | AML1; AMLCR1; CBF-alpha-2; CBFA2; EVI-1; OTTHUMP00000108697; PEBP2A2; PEBP2aB |
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