Rb (RB1) Rabbit Polyclonal Antibody
CAT#: TA380744
RB Rabbit polyclonal Antibody
Size: 20 ul
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CNY 1,999.00
CNY 3,280.00
货期*
2周
规格
经常一起买 (1)
Specifications
Product Data | |
Applications | ICC/IF, WB |
Recommend Dilution | WB,1:500 - 1:2000 IF,1:50 - 1:200 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | Recombinant protein of human RB |
Formulation | Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |
Concentration | lot specific |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage Condition | Store at -20℃. Avoid freeze / thaw cycles. |
Predicted Protein Size | 106kDa |
Gene Name | RB transcriptional corepressor 1 |
Database Link | |
Background | The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma. |
Synonyms | OSRC; osteosarcoma; p105-Rb; pp110; pRb; RB |
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