Nucleophosmin (NPM1) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB,1:500 - 1:2000
Reactivity	Human
Modifications	Phospho T199
Host	Rabbit
Clonality	Polyclonal
Immunogen	A synthetic phosphorylated peptide around T199 of human NPM1 (NP_001032827.1).
Formulation	PBS with 0.05% proclin300,50% glycerol,pH7.3.
Concentration	lot specific
Purification	Affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20℃. Avoid freeze / thaw cycles.
Predicted Protein Size	28kDa/29kDa/32kDa
Gene Name	nucleophosmin (nucleolar phosphoprotein B23, numatrin)
Database Link	Entrez Gene 4869 Human UniProt ID P06748
Background	This gene encodes a phosphoprotein which moves between the nucleus and the cytoplasm. The gene product is thought to be involved in several processes including regulation of the ARF/p53 pathway. A number of genes are fusion partners have been characterized, in particular the anaplastic lymphoma kinase gene on chromosome 2. Mutations in this gene are associated with acute myeloid leukemia. More than a dozen pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript variants.
Synonyms	B23; MGC104254; NPM; Numatrin
Reference Data

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