JNK1 (MAPK8) Rabbit Polyclonal Antibody
CAT#: TA378316
Phospho-JNK1/2-T183/Y185 Rabbit polyclonal Antibody
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CNY 2,900.00
货期*
2周
规格
经常一起买 (1)
beta Actin Mouse Monoclonal Antibody, Clone OTI1, Loading Control
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Specifications
Product Data | |
Applications | WB |
Recommend Dilution | WB,1:500 - 1:2000 |
Reactivity | Human, Mouse, Rat |
Modifications | Phospho T183/Y185 |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | A synthetic phosphorylated peptide around T183 of human JNK1 (NP_620637.1). |
Formulation | PBS with 0.05% proclin300,50% glycerol,pH7.3. |
Concentration | lot specific |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage Condition | Store at -20℃. Avoid freeze / thaw cycles. |
Predicted Protein Size | 35kDa/44kDa/48kDa/27kDa |
Gene Name | mitogen-activated protein kinase 8 |
Database Link | |
Background | The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various cell stimuli, and targets specific transcription factors, and thus mediates immediate-early gene expression in response to cell stimuli. The activation of this kinase by tumor-necrosis factor alpha (TNF-alpha) is found to be required for TNF-alpha induced apoptosis. This kinase is also involved in UV radiation induced apoptosis, which is thought to be related to cytochrom c-mediated cell death pathway. Studies of the mouse counterpart of this gene suggested that this kinase play a key role in T cell proliferation, apoptosis and differentiation. Several alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Apr 2016] |
Synonyms | JNK; JNK-46; JNK1; JNK1A2; JNK21B1/2; OTTHUMP00000019552; PRKM8; SAPK1 |
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