Histone H2A.X (H2AFX) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB,1:500 - 1:1000
Reactivity	Human, Mouse, Rat
Modifications	Phospho S139
Host	Rabbit
Clonality	Polyclonal
Immunogen	A synthetic phosphorylated peptide around S139 of human Histone H2AX (NP_002096.1).
Formulation	Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Concentration	lot specific
Purification	Affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20℃. Avoid freeze / thaw cycles.
Predicted Protein Size	15kDa
Gene Name	H2A histone family member X
Database Link	Entrez Gene 3014 Human UniProt ID P16104
Background	Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a replication-independent histone that is a member of the histone H2A family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif.
Synonyms	H2A.X; H2A/X; H2AX
Reference Data

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