c Fos (FOS) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB,1:500 - 1:2000
Reactivity	Human, Mouse, Rat
Modifications	Phospho T232
Host	Rabbit
Clonality	Polyclonal
Immunogen	A synthetic phosphorylated peptide around T232 of human c-Fos (NP_005243.1).
Formulation	Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Concentration	lot specific
Purification	Affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20℃. Avoid freeze / thaw cycles.
Predicted Protein Size	28kDa/36kDa/40kDa
Gene Name	Fos proto-oncogene, AP-1 transcription factor subunit
Database Link	Entrez Gene 2353 Human UniProt ID P01100
Background	The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. In some cases, expression of the FOS gene has also been associated with apoptotic cell death.
Synonyms	AP-1; C-FOS; G0S7
Reference Data

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