Filamin A (FLNA) Rabbit Polyclonal Antibody

CAT#: TA376275

Filamin A Rabbit polyclonal Antibody



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CNY 1,999.00

CNY 3,280.00


货期*
2周

规格
    • 100 ul

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经常一起买 (1)
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Specifications

Product Data
Applications ICC/IF, IHC, WB
Recommend Dilution WB,1:500 - 1:2000
IHC,1:50 - 1:200
IF,1:50 - 1:200
Reactivity Human, Mouse, Rat
Modifications Unmodified
Host Rabbit
Clonality Polyclonal
Immunogen A synthetic peptide corresponding to a sequence within amino acids 2500 to the C-terminus of human Filamin A (NP_001104026.1).
Formulation Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Concentration lot specific
Purification Affinity purification
Conjugation Unconjugated
Storage Condition Store at -20℃. Avoid freeze / thaw cycles.
Predicted Protein Size 280kDa
Gene Name filamin A
Background The protein encoded by this gene is an actin-binding protein that crosslinks actin filaments and links actin filaments to membrane glycoproteins. The encoded protein is involved in remodeling the cytoskeleton to effect changes in cell shape and migration. This protein interacts with integrins, transmembrane receptor complexes, and second messengers. Defects in this gene are a cause of several syndromes, including periventricular nodular heterotopias (PVNH1, PVNH4), otopalatodigital syndromes (OPD1, OPD2), frontometaphyseal dysplasia (FMD), Melnick-Needles syndrome (MNS), and X-linked congenital idiopathic intestinal pseudoobstruction (CIIPX). Two transcript variants encoding different isoforms have been found for this gene.
Synonyms ABP-280; ABPX; Alpha-filamin; DKFZp434P031; Filamin-1; FLN; FLN1; FMD; MNS; NHBP; OPD; OPD1; OPD2
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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