Dystonin (DST) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB,1:500 - 1:2000 IHC,1:50 - 1:200
Reactivity	Human, Mouse, Rat
Modifications	Unmodified
Host	Rabbit
Clonality	Polyclonal
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 1-270 of human DST (NP_001714.1).
Formulation	Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Concentration	lot specific
Purification	Affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20℃. Avoid freeze / thaw cycles.
Predicted Protein Size	9kDa/25kDa/50kDa/102kDa/306-860kDa
Gene Name	dystonin
Database Link	Entrez Gene 667 Human UniProt ID Q03001
Background	This gene encodes a member of the plakin protein family of adhesion junction plaque proteins. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene, but the full-length nature of some variants has not been defined. It has been reported that some isoforms are expressed in neural and muscle tissue, anchoring neural intermediate filaments to the actin cytoskeleton, and some isoforms are expressed in epithelial tissue, anchoring keratin-containing intermediate filaments to hemidesmosomes. Consistent with the expression, mice defective for this gene show skin blistering and neurodegeneration.
Synonyms	BP240; BPA; BPAG1; CATX-15; D6S1101; DKFZp564B2416; DMH; DT; dystonin; FLJ13425; FLJ21489; FLJ30627; FLJ32235; FLJ46791; KIAA0465; KIAA0728; KIAA1470; MACF2; trabeculin-beta
Reference Data

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