DNMT1 Rabbit Polyclonal Antibody
CAT#: TA375561
DNMT1 Rabbit polyclonal Antibody
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CNY 2,700.00
货期*
2周
规格
经常一起买 (1)
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Specifications
Product Data | |
Applications | ICC/IF, IHC, IP, WB |
Recommend Dilution | WB,1:500 - 1:2000 IHC,1:50 - 1:200 IF,1:50 - 1:200 IP,1:50 - 1:100 |
Reactivity | Human, Mouse, Rat |
Modifications | Unmodified |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | Recombinant protein of human DNMT1. |
Formulation | Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |
Concentration | lot specific |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage Condition | Store at -20℃. Avoid freeze / thaw cycles. |
Predicted Protein Size | 144kDa/183kDa/184kDa |
Gene Name | DNA (cytosine-5-)-methyltransferase 1 |
Database Link | |
Background | This gene encodes an enzyme that transfers methyl groups to cytosine nucleotides of genomic DNA. This protein is the major enzyme responsible for maintaining methylation patterns following DNA replication and shows a preference for hemi-methylated DNA. Methylation of DNA is an important component of mammalian epigenetic gene regulation. Aberrant methylation patterns are found in human tumors and associated with developmental abnormalities. Variation in this gene has been associated with cerebellar ataxia, deafness, and narcolepsy, and neuropathy, hereditary sensory, type IE. Alternative splicing results in multiple transcript variants. |
Synonyms | AIM; CXXC9; DNMT; FLJ16293; M.HsaI; MCMT; MGC104992 |
Reference Data |
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