BCAR1 Rabbit Polyclonal Antibody

CAT#: TA373954

Phospho-BCAR1-Y410 Rabbit polyclonal Antibody



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CNY 2,900.00


货期*
2周

规格
    • 100 ul

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Specifications

Product Data
Applications WB
Recommend Dilution WB,1:500 - 1:2000
Reactivity Human, Mouse
Modifications Phospho Y410
Host Rabbit
Clonality Polyclonal
Immunogen A phospho synthetic peptide corresponding to residues surrounding Y410 of human BCAR1.
Formulation Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Concentration lot specific
Purification Affinity purification
Conjugation Unconjugated
Storage Condition Store at -20℃. Avoid freeze / thaw cycles.
Predicted Protein Size 93kDa
Gene Name BCAR1, Cas family scaffolding protein
Background The protein encoded by this gene is a member of the Crk-associated substrate (CAS) family of scaffold proteins, characterized by the presence of multiple protein-protein interaction domains and many serine and tyrosine phosphorylation sites. The encoded protein contains a Src-homology 3 (SH3) domain, a proline-rich domain, a substrate domain which contains 15 repeat of the YxxP consensus phosphorylation motif for Src family kinases, a serine-rich domain, and a bipartite Src-binding domain, which can bind both SH2 and SH3 domains. This adaptor protein functions in multiple cellular pathways, including in cell motility, apoptosis and cell cycle control. Dysregulation of this gene can have a wide range of effects, affecting different pathways, including cardiac development, vascular smooth muscle cells, liver and kidney function, endothelial migration, and cancer.
Synonyms CAS; CAS1; CASS1; CRKAS; FLJ12176; FLJ45059; P130Cas
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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