Apc5 (ANAPC5) Rabbit Polyclonal Antibody

CAT#: TA373504

ANAPC5 Rabbit polyclonal Antibody



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CNY 2,700.00


货期*
2周

规格
    • 100 ul

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Specifications

Product Data
Applications IHC, IP, WB
Recommend Dilution WB,1:500 - 1:2000
IHC,1:50 - 1:200
IP,1:50 - 1:100
Reactivity Human, Mouse, Rat
Modifications Unmodified
Host Rabbit
Clonality Polyclonal
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human ANAPC5 (NP_057321.2).
Formulation Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Concentration lot specific
Purification Affinity purification
Conjugation Unconjugated
Storage Condition Store at -20℃. Avoid freeze / thaw cycles.
Predicted Protein Size 25kDa/72kDa/85kDa
Gene Name anaphase promoting complex subunit 5
Background This gene encodes a tetratricopeptide repeat-containing component of the anaphase promoting complex/cyclosome (APC/C), a large E3 ubiquitin ligase that controls cell cycle progression by targeting a number of cell cycle regulators such as B-type cyclins for 26S proteasome-mediated degradation through ubiquitination. The encoded protein is required for the proper ubiquitination function of APC/C and for the interaction of APC/C with transcription coactivators. It also interacts with polyA binding protein and represses internal ribosome entry site-mediated translation. Multiple transcript variants encoding different isoforms have been found for this gene. These differences cause translation initiation at a downstream AUG and result in a shorter protein (isoform b), compared to isoform a.
Synonyms APC5
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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