Activin A Receptor Type IC (ACVR1C) Rabbit Polyclonal Antibody
CAT#: TA373240
ACVR1C Rabbit polyclonal Antibody
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货期*
2周
规格
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Specifications
Product Data | |
Applications | IHC, WB |
Recommend Dilution | WB,1:500 - 1:2000 IHC,1:100 - 1:200 |
Reactivity | Human, Mouse, Rat |
Modifications | Unmodified |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 22-113 of human ACVR1C (NP_660302.2). |
Formulation | Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |
Concentration | lot specific |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage Condition | Store at -20℃. Avoid freeze / thaw cycles. |
Predicted Protein Size | 37kDa/46kDa/49kDa/54kDa |
Gene Name | activin A receptor type 1C |
Database Link | |
Background | ACVR1C is a type I receptor for the TGFB (see MIM 190180) family of signaling molecules. Upon ligand binding, type I receptors phosphorylate cytoplasmic SMAD transcription factors, which then translocate to the nucleus and interact directly with DNA or in complex with other transcription factors (Bondestam et al., 2001 [PubMed 12063393]).[supplied by OMIM, Mar 2008] |
Synonyms | ACTR-IC; ACVRLK7; ALK-7; ALK7 |
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