UBQLN2 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	WB: 500-2000 WB positive control: SKOV3 cell lysate IHC: 30-150 Positive control: Human thyroid cancer Predicted cell location: Cytoplasm and Nucleus
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide of human UBQLN2
Formulation	pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C.
Predicted Protein Size	66 kDa
Gene Name	ubiquilin 2
Database Link	Entrez Gene 29978 Human UniProt ID Q9UHD9
Background	This gene encodes an ubiquitin-like protein (ubiquilin) that shares high degree of similarity with related products in yeast, rat and frog. Ubiquilins contain a N-terminal ubiquitin-like domain and a C-terminal ubiquitin-associated domain. They physically associate with both proteasomes and ubiquitin ligases; and thus, are thought to functionally link the ubiquitination machinery to the proteasome to affect in vivo protein degradation. This ubiquilin has also been shown to bind the ATPase domain of the Hsp70-like Stch protein.
Synonyms	Chap1; CHAP1/DSK2; Dsk2; FLJ10167; FLJ56541; hPLIC-2; HRIHFB2157; LIC-2; N4BP4; PLIC-2; PLIC2; RIHFB2157
Reference Data

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