AGPAT2 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	WB: 500-2000 WB positive control: K562, A549, 231, PC3 cell lysates IHC: 50-200 Positive control: Human esophagus cancer Predicted cell location: Cytoplasm and Cell membrane
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide of human AGPAT2
Formulation	pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C.
Predicted Protein Size	31 kDa
Gene Name	1-acylglycerol-3-phosphate O-acyltransferase 2
Database Link	Entrez Gene 10555 Human UniProt ID O15120
Background	This gene encodes a member of the 1-acylglycerol-3-phosphate O-acyltransferase family. The protein is located within the endoplasmic reticulum membrane and converts lysophosphatidic acid to phosphatidic acid, the second step in de novo phospholipid biosynthesis. Mutations in this gene have been associated with congenital generalized lipodystrophy (CGL), or Berardinelli-Seip syndrome, a disease characterized by a near absence of adipose tissue and severe insulin resistance. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Synonyms	1-AGPAT2; BSCL; BSCL1; LPAAB; LPAAT-beta
Reference Data

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