EXD2 Rabbit Polyclonal Antibody
CAT#: TA370385
EXD2 rabbit polyclonal antibody
Size: 25 ul
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CNY 1,999.00
CNY 3,280.00
CNY 300.00
CNY 1,430.00
Specifications
Product Data | |
Applications | IHC, WB |
Recommend Dilution | WB: 500-2000 WB positive control: Mouse brain tissue and Human cerebrum tissue lysates IHC: 40-200 Positive control: Human tonsil Predicted cell location: Cytoplasm or Nucleus |
Reactivity | Human, Mouse |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | Fusion protein of human EXD2 |
Formulation | pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Concentration | lot specific |
Purification | Antigen affinity purification |
Conjugation | Unconjugated |
Storage Condition | Store at -20°C. |
Predicted Protein Size | 70 kDa |
Gene Name | exonuclease 3'-5' domain containing 2 |
Database Link | |
Background | Exonuclease required for double-strand breaks resection and efficient homologous recombination. Plays a key role in controlling the initial steps of chromosomal break repair, it is recruited to chromatin in a damage-dependent manner and functionally interacts with the MRN complex to accelerate resection through its 3'-5' exonuclease activity, which efficiently processes double-stranded DNA substrates containing nicks. |
Synonyms | C14orf114; DKFZp781A0133; DKFZp781L15100; EXDL2; FLJ10738; OTTHUMP00000205813; OTTHUMP00000205816; OTTHUMP00000205817; OTTHUMP00000205818 |
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