MDFI Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	WB: 500-2000 WB positive control: Human placenta tissue lysate IHC: 50-300 Positive control: Human esophagus cancer Predicted cell location: Nucleus
Reactivity	Human, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Fusion protein of human MDFI
Formulation	pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C.
Predicted Protein Size	25 kDa
Gene Name	MyoD family inhibitor
Database Link	Entrez Gene 4188 Human UniProt ID Q99750
Background	This protein is a transcription factor that negatively regulates other myogenic family proteins. Studies of the mouse homolog, I-mf, show that it interferes with myogenic factor function by masking nuclear localization signals and preventing DNA binding. Knockout mouse studies show defects in the formation of vertebrae and ribs that also involve cartilage formation in these structures.
Synonyms	I-MF; I-mfa; OTTHUMP00000196414
Reference Data

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