INAVA Rabbit Polyclonal Antibody

CAT#: TA369871S

INAVA rabbit polyclonal antibody

Size: 25 ul 100 ul



Need it in bulk or conjugated?
Get a free quote

CNY 800.00

CNY 1,280.00


货期*
2周

规格
    • 25 ul

Product images

经常一起买 (1)
beta Actin Mouse Monoclonal Antibody, Clone OTI1, Loading Control
    • 30 ul

CNY 300.00
CNY 1,430.00

Specifications

Product Data
Applications IHC
Recommend Dilution IHC: 50-300
Positive control: Human liver cancer
Predicted cell location: Cytoplasm and Cell membrane
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Immunogen Fusion protein of human INAVA
Formulation pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Antigen affinity purification
Conjugation Unconjugated
Storage Condition Store at -20°C.
Gene Name chromosome 1 open reading frame 106
Background Expressed in peripheral macrophages and intestinal myeloid-derived cells, is required for optimal PRR (pattern recognition receptor)-induced signaling, cytokine secretion, and bacterial clearance. Upon stimulation of a broad range of PRRs (pattern recognition receptor) such as NOD2 or TLR2, TLR3, TLR4, TLR5, TLR7 and TLR9, associates with YWHAQ/14-3-3T, which in turn leads to the recruitment and activation of MAP kinases and NF-kappa-B signaling complexes that amplifies PRR-induced downstream signals and cytokine secretion (PubMed:28436939). In the intestine, regulates adherens junction stability by regulating the degradation of CYTH1 and CYTH2, probably acting as substrate cofactor for SCF E3 ubiquitin-protein ligase complexes. Stabilizes adherens junctions by limiting CYTH1-dependent ARF6 activation (PubMed:29420262).
Synonyms FLJ10901; MGC125608
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
Customer Reviews 
Loading...