CTNNAL1 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB: 200-1000 WB positive control: A431 cell lysate
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	Fusion protein of human CTNNAL1
Formulation	pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C.
Predicted Protein Size	82 kDa
Gene Name	catenin alpha like 1
Database Link	Entrez Gene 8727 Human UniProt ID Q9UBT7
Background	CTNNAL1 (catenin (cadherin-associated protein), alpha-like 1), also known as CLLP or alpha-CATU, is a 734 amino acid cytoplasmic peripheral membrane protein belonging to the vinculin/alpha-catenin family. Expressed at high levels in adrenal gland and present at lower levels in neural tissues, CTNNAL1 may be involved in the regulation of Rho pathway signaling by providing a scaffold for the Lbc Rho guanine nucleotide exchange factor 1 (RhoGEF p115). It is suggested that CTNNAL1 is down-regulated in pancreatic carcinoma undergoing differentiation and apoptosis. Existing as three isforms produced by alternative splicing events, CTNNAL1 may contribute to the wound repair and proliferation of human bronchial epithelial cells (HBEC).
Synonyms	ACRP; alpha-CATU; alpha-catulin; alpha2-catulin; CLLP; FLJ08121
Reference Data

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