Calpain 7 (CAPN7) Rabbit Polyclonal Antibody
CAT#: TA368764S
CAPN7 rabbit polyclonal antibody
Size: 100 ul
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Specifications
Product Data | |
Applications | IHC, WB |
Recommend Dilution | WB: 500-2000 WB positive control: Human normal liver and mouse liver tissue, mouse intestines and pancreas tissue, hepg2 and HT-29 cells, mouse heart tissue IHC: 25-100 Positive control: Human liver cancer Predicted cell location: Cytoplasm and Cell membrane |
Reactivity | Human, Mouse |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | Fusion protein of human CAPN7 |
Formulation | pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Purification | Antigen affinity purification |
Conjugation | Unconjugated |
Storage Condition | Store at -20°C. |
Predicted Protein Size | 93 kDa |
Gene Name | calpain 7 |
Database Link | |
Background | Calpains are ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. The calpain proteins are heterodimers consisting of an invariant small subunit and variable large subunits. The large subunit possesses a cysteine protease domain, and both subunits possess calcium-binding domains. Calpains have been implicated in neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress. The function of the protein encoded by this gene is not known. An orthologue has been found in mouse but it seems to diverge from other family members. The mouse orthologue is thought to be calcium independent with protease activity. |
Synonyms | CALPAIN7; FLJ36423; PALBH |
Reference Data |
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