glucose 6 phosphatase, catalytic subunit (G6PC) Rabbit Polyclonal Antibody
CAT#: TA368608S
G6PC1 rabbit polyclonal antibody
Size: 100 ul
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CNY 800.00
CNY 1,280.00
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CNY 1,430.00
Specifications
Product Data | |
Applications | IHC |
Recommend Dilution | IHC: 50-300 Positive control: Human liver cancer Predicted cell location: Cytoplasm |
Reactivity | Human, Mouse, Rat |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | Synthetic peptide of human G6PC1 |
Formulation | pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Purification | Antigen affinity purification |
Conjugation | Unconjugated |
Storage Condition | Store at -20°C. |
Gene Name | glucose-6-phosphatase catalytic subunit |
Database Link | |
Background | Glucose-6-phosphatase (G6Pase) is a multi-subunit integral membrane protein of the endoplasmic reticulum that is composed of a catalytic subunit and transporters for G6P, inorganic phosphate, and glucose. This gene (G6PC) is one of the three glucose-6-phosphatase catalytic-subunit-encoding genes in human: G6PC, G6PC2 and G6PC3. Glucose-6-phosphatase catalyzes the hydrolysis of D-glucose 6-phosphate to D-glucose and orthophosphate and is a key enzyme in glucose homeostasis, functioning in gluconeogenesis and glycogenolysis. Mutations in this gene cause glycogen storage disease type I (GSD1). This disease, also known as von Gierke disease, is a metabolic disorder characterized by severe hypoglycemia associated with the accumulation of glycogen and fat in the liver and kidneys. |
Synonyms | G-6-Pase; G6Pase; G6Pase-alpha; G6PT; GSD1; GSD1a; MGC163350 |
Reference Data |
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