IKAP (IKBKAP) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	WB: 200-1000 WB positive control: 231, K562 and A172 cell lysates IHC: 25-100 Positive control: Human tonsil Predicted cell location: Cytoplasm
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide of human ELP1
Formulation	pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C.
Predicted Protein Size	150 kDa
Gene Name	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein
Database Link	Entrez Gene 8518 Human UniProt ID O95163
Background	The protein encoded by this gene is a scaffold protein and a regulator for three different kinases involved in proinflammatory signaling. The encoded protein can bind NF-kappa-B-inducing kinase and I-kappa-B kinases through separate domains and assemble them into an active kinase complex. Mutations in this gene have been associated with familial dysautonomia. Alternative splicing results in multiple transcript variants encoding different isoforms.
Synonyms	DKFZp781H1425; DYS; ELP1; FD; FLJ12497; IKAP; IKI3; p150; TOT1
Reference Data

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