WDSUB1 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB: 500-2000 WB positive control: 293T，NIH/3T3 and K562 cell lysates
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide of human WDSUB1
Formulation	pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C.
Predicted Protein Size	53 kDa
Gene Name	WD repeat, sterile alpha motif and U-box domain containing 1
Database Link	Entrez Gene 151525 Human UniProt ID Q8N9V3
Background	WDSUB1 (WD repeat, SAM and U-box domain-containing protein 1), also known as UBOX6 or WDSAM1, is a 476 amino acid protein that contains one SAM (sterile alpha motif) domain, one U-box domain and seven WD repeats. Existing as two isoforms due to alternative splicing, WDSUB1 is encoded by a gene located on chromosome 2. The second largest human chromosome, chromosome 2 encodes over 1,400 genes and comprises nearly 8% of the human genome, housing a number of disease-associated genes. Harlequin icthyosis, a rare and morbid skin deformity, is associated with mutations in the ABCA12 gene, while the lipid metabolic disorder sitosterolemia is associated with defects in the ABCG5 and ABCG8 genes. Additionally, an extremely rare recessive genetic disorder, Alström syndrome, is caused by mutations in the ALMS1 gene, which maps to chromosome 2.
Synonyms	2610014F08Rik; FLJ36175; UBOX6; WDSAM1
Reference Data

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