TFII I (GTF2I) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	WB: 500-2000 WB positive control: Hela, 293T, Raji and 231 cells IHC: 50-200 Positive control: Human liver cancer Predicted cell location: Nucleus
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide of human GTF2I
Formulation	pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C.
Predicted Protein Size	112 kDa
Gene Name	general transcription factor IIi
Database Link	Entrez Gene 2969 Human UniProt ID P78347
Background	This gene encodes a phosphoprotein containing six characteristic repeat motifs. The encoded protein binds to the initiator element (Inr) and E-box element in promoters and functions as a regulator of transcription. This locus, along with several other neighboring genes, is deleted in Williams-Beuren syndrome. There are many closely related genes and pseudogenes for this gene on chromosome 7. This gene also has pseudogenes on chromosomes 9, 13, and 21. Alternatively spliced transcript variants encoding multiple isoforms have been observed.
Synonyms	BAP-135; BAP135; BTKAP1; DIWS; FLJ38776; FLJ56355; GTFII-I; IB291; OTTHUMP00000209509; SPIN; TFII-I; WBS; WBSCR6
Reference Data

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