CGREF1 Rabbit Polyclonal Antibody

CAT#: TA365633

CGREF1 rabbit polyclonal antibody

Size: 25 ul 100 ul



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CNY 1,999.00

CNY 3,280.00


货期*
2周

规格
    • 100 ul

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Specifications

Product Data
Applications IHC
Recommend Dilution IHC: 25-100
Positive control: Human thyroid cancer
Predicted cell location: Cytoplasm and Cell membrane
Reactivity Human
Host Rabbit
Clonality Polyclonal
Immunogen Fusion protein of human CGREF1
Formulation pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Concentration lot specific
Purification Antigen affinity purification
Conjugation Unconjugated
Storage Condition Store at -20°C.
Gene Name cell growth regulator with EF-hand domain 1
Background CGREF1 (cell growth regulator with EF-hand domain 1), also known as CGR11, is a 301 amino acid secreted protein that contains two highly conserved calcium binding EF-hand domains, which are required for mediating cell-cell adhesion. Induced by p53, CGREF1 is able to inhibit cell growth in various cell lines. CGREF1 is encoded by a gene located on human chromosome 2, which houses over 1,400 genes and comprises nearly 8% of the human genome. Harlequin icthyosis, a rare and morbid skin deformity, is associated with mutations in the ABCA12 gene, while the lipid metabolic disorder sitosterolemia is associated with defects in the ABCG5 and ABCG8 genes. Additionally, an extremely rare recessive genetic disorder, Alstrωm syndrome, is caused by mutations in the ALMS1 gene, which maps to chromosome 2.
Synonyms CGR11; Hydrophobestin
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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