Tubulin Polymerization Promoting Protein (TPPP) Rabbit Polyclonal Antibody

CAT#: TA365281S

TPPP rabbit polyclonal antibody

Size: 25 ul 100 ul



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CNY 800.00

CNY 1,280.00


货期*
2周

规格
    • 25 ul

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Specifications

Product Data
Applications IHC, WB
Recommend Dilution WB: 200-1000
WB positive control: Mouse brain tissue and Rat brain tissue
IHC: 25-100
Positive control: Human lung cancer
Predicted cell location: Cytoplasm or Nucleus
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Immunogen Full length fusion protein
Formulation pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Antigen affinity purification
Conjugation Unconjugated
Storage Condition Store at -20°C.
Predicted Protein Size 24 kDa
Gene Name tubulin polymerization promoting protein
Background Tubulin family members are globular proteins important in the assembly of microtubules. Microtubules are structural components that play important roles in mitosis, cytokinesis and vesicle transport. TPPP (Tubulin polymerization-promoting protein), also known as p24 and p25, is a widely expressed 219 amino acid protein found in the perinuclear region of the cytoplasm. TPPP may form dimers and functions in polymerizing tubulin into double-walled tubules, polymorphic aggregates, or stabilized blocks. TPPP overexpression prevents formation of the mitotic spindle assembly and breakdown of the nuclear envelope. TPPP is phosphorylated by TPK II and is encoded by a gene that maps to human chromosome 5, which contains 181 million base pairs and comprises nearly 6% of the human genome. May play a role in the polymerization of tubulin into microtubules, microtubule bundling and the stabilization of existing microtubules, thus maintaining the integrity of the microtubule network. May play a role in mitotic spindle assembly and nuclear envelope breakdown.
Synonyms p24; p25; p25-alpha; p25alpha; TPPP/p25; TPPP1
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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