Hydroxysteroid (17 beta) Dehydrogenase 4 (HSD17B4) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	WB: 500-2000 WB positive control: Huvec and K562 cells IHC: 50-200 Positive control: Human colon cancer Predicted cell location: Cytoplasm
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Fusion protein of human HSD17B4
Formulation	pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C.
Predicted Protein Size	80 kDa
Gene Name	hydroxysteroid (17-beta) dehydrogenase 4
Database Link	Entrez Gene 3295 Human UniProt ID P51659
Background	The protein encoded by this gene is a bifunctional enzyme that is involved in the peroxisomal beta-oxidation pathway for fatty acids. It also acts as a catalyst for the formation of 3-ketoacyl-CoA intermediates from both straight-chain and 2-methyl-branched-chain fatty acids. Defects in this gene that affect the peroxisomal fatty acid beta-oxidation activity are a cause of D-bifunctional protein deficiency (DBPD). An apparent pseudogene of this gene is present on chromosome 8.
Synonyms	3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholest; beta-keto-reductase; DBP; EDH17B4; MFE-2; SDR8C1
Reference Data

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