Hamp Rabbit Polyclonal Antibody
CAT#: TA364352
Rabbit polyclonal anti Hepcidin-25 (ms); purified rabbit IgG
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CNY 11,419.00
货期*
5周
规格
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Specifications
Product Data | |
Applications | ELISA |
Recommend Dilution | This antibody has been tested and validated in ELISA against Hepcidin- 25. Other applications like immunohistochemistry (IHC), FACS or Western Blot may work as well. Optimal dilutions should be determined by the end user. |
Reactivity | Mouse |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | Synthetic peptide H-Asp-Thr-Asn-Phe-Pro-Ile-Cys-Leu-Phe-Cys-Cys- Lys-Cys-Cys-Lys-Asn-Ser-Ser-Cys-Gly-Leu-Cys-Cys-Ile-Thr-OH coupled to carrier protein. |
Formulation | Protein A affinity purified from antiserum, lyophilized, packaged under nitrogen. Reconstitute by adding 0.2ml distilled water. This stock solution contains 2mg/ml IgG, phosphate buffer saline pH 7.4 (PBS), and 0.02% (w/v) Thimerosal as a preservative. |
Concentration | N/A |
Conjugation | Unconjugated |
Storage Condition | Original vial: at least one year at 4° - 8°C from date of delivery. Minimize repeated thawing and freezing of the antiserum by freezing aliquots at -20°C or below. |
Gene Name | hepcidin antimicrobial peptide |
Database Link | |
Background | Hepcidin-25 is a 25-residue peptide synthesized in the liver. This is the bioactive form of hepcidin, a key regulator of iron homeostasis. It acts through downregulation of the cellular iron exporter ferroportin, which is expressed on enterocytes, macrophages and hepatocytes. Hepcidin-25 production is upregulated by inflammation as well as iron overload, leading to anemia through interference with the body's intestinal iron absorption and its utilization of iron. Hepcidin is also a small defensin-like peptide with anti-microbial activity, which is secreted into the urine. This antibody was generated by immunization of rabbits with Hepcidin-25 coupled to a carrier protein. |
Synonyms | HEPC; HEPCIDIN; HFE2; HFE2B; LEAP-1; LEAP1; PLTR |
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