Hamp Rabbit Polyclonal Antibody

CAT#: TA364352

Rabbit polyclonal anti Hepcidin-25 (ms); purified rabbit IgG



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CNY 11,419.00


货期*
5周

规格
    • 400 ug

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Specifications

Product Data
Applications ELISA
Recommend Dilution This antibody has been tested and validated in ELISA against Hepcidin- 25. Other applications like immunohistochemistry (IHC), FACS or Western Blot may work as well. Optimal dilutions should be determined by the end user.
Reactivity Mouse
Host Rabbit
Clonality Polyclonal
Immunogen Synthetic peptide H-Asp-Thr-Asn-Phe-Pro-Ile-Cys-Leu-Phe-Cys-Cys- Lys-Cys-Cys-Lys-Asn-Ser-Ser-Cys-Gly-Leu-Cys-Cys-Ile-Thr-OH coupled to carrier protein.
Formulation Protein A affinity purified from antiserum, lyophilized, packaged under nitrogen. Reconstitute by adding 0.2ml distilled water. This stock solution contains 2mg/ml IgG, phosphate buffer saline pH 7.4 (PBS), and 0.02% (w/v) Thimerosal as a preservative.
Concentration N/A
Conjugation Unconjugated
Storage Condition Original vial: at least one year at 4° - 8°C from date of delivery. Minimize repeated thawing and freezing of the antiserum by freezing aliquots at -20°C or below.
Gene Name hepcidin antimicrobial peptide
Background Hepcidin-25 is a 25-residue peptide synthesized in the liver. This is the bioactive form of hepcidin, a key regulator of iron homeostasis. It acts through downregulation of the cellular iron exporter ferroportin, which is expressed on enterocytes, macrophages and hepatocytes. Hepcidin-25 production is upregulated by inflammation as well as iron overload, leading to anemia through interference with the body's intestinal iron absorption and its utilization of iron. Hepcidin is also a small defensin-like peptide with anti-microbial activity, which is secreted into the urine. This antibody was generated by immunization of rabbits with Hepcidin-25 coupled to a carrier protein.
Synonyms HEPC; HEPCIDIN; HFE2; HFE2B; LEAP-1; LEAP1; PLTR
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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