prothymosin, alpha (PTMA) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	ELISA
Recommend Dilution	This antibody has been tested and validated in ELISA against Thymosin α-1. Other applications like immunohistochemistry (IHC), FACS or Western Blot may work as well. Optimal dilutions should be determined by the end user.
Reactivity	Human, Mammalian
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide Ac-Ser-Asp-Ala-Ala-Asp-Thr-Ser-Ser-Glu-Ile-Thr-Thr- Lys-Asp-Leu-Lys-Glu-Val-Val-Glu-Glu-Ala-Glu-Asn-OH coupled to a carrier protein.
Formulation	Protein A affinity purified from antiserum, lyophilized, packaged under nitrogen. Reconstitute by adding 0.2ml distilled water. This stock solution contains 2mg/ml IgG, phosphate buffer saline pH 7.4 (PBS), and 0.02% (w/v) Thimerosal as a preservative.
Concentration	N/A
Conjugation	Unconjugated
Storage Condition	Original vial: at least one year at 4° - 8°C from date of delivery. Minimize repeated thawing and freezing of the antiserum by freezing aliquots at -20°C or below.
Gene Name	prothymosin, alpha
Database Link	Entrez Gene 5757 Human UniProt ID P06454
Background	Thymosins are small proteins isolated from the thymus, but most are now known to be also present in many other tissues. Thymosins have diverse biological activities, and two in particular, thymosins α1 and β4, have potentially important uses in medicine. Thymosin α-1 is a 28-amino acids peptide fragment derived from prothymosin alpha, a protein that in humans is encoded by the PTMA gene and it is believed to be a major component of Thymosin Fraction 5 responsible for the activity of that preparation in restoring immune function in animals lacking thymus glands. Thymosin β-4 is a 43-amino acids protein that in humans is encoded by the TMSB4X gene. It is a major cellular constituent in many tissues. Its intracellular concentration may reach as high as 0.5 mM. Following Thymosin α1, β4 was the second of the biologically active peptides from Thymosin Fraction 5 to be completely sequenced and synthesized. This antibody was generated by immunization of rabbits with Thymosin α-1 coupled to a carrier protein.
Synonyms	MGC104802; TMSA
Reference Data

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.