Pth Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	ELISA
Recommend Dilution	This antibody has been tested and validated in ELISA against pTH (1- 34). Other applications like immunohistochemistry (IHC), FACS or Western Blot may work as well. Optimal dilutions should be determined by the end user.
Reactivity	Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide H-Ala-Val-Ser-Glu-Ile-Gln-Leu-Met-His-Asn-Leu-Gly- Lys-His-Leu-Ala-Ser-Val-Glu-Arg-Met-Gln-Trp-Leu-Arg-Lys-Lys-Leu-Gln- Asp-Val-His-Asn-Phe-OH (Disulfide bond) coupled to carrier protein.
Formulation	Protein A affinity purified from antiserum, lyophilized, packaged under nitrogen. Reconstitute by adding 0.2ml distilled water. This stock solution contains 2mg/ml IgG, phosphate buffer saline pH 7.4 (PBS), and 0.02% (w/v) Thimerosal as a preservative.
Concentration	N/A
Conjugation	Unconjugated
Storage Condition	Original vial: at least one year at 4° - 8°C from date of delivery. Minimize repeated thawing and freezing of the antiserum by freezing aliquots at -20°C or below.
Gene Name	parathyroid hormone
Database Link	Entrez Gene 24694 Rat UniProt ID P04089
Background	Parathyroid Hormone (pTH) (1-34), is a peptide fragment of the naturally occurring human parathyroid hormone and is secreted from cells of the parathyroid glands and finds its major target cells in bone and kidney. It is an important regulator of calcium and phosphorus metabolism, playing a role in calcium homeostasis of bone, kidney, breast, and placenta. pTH (1-34) administration suppresses cardiovascular calcification and down-regulates aortic osteogenic programs driven by diabetes and dyslipidemia. This antibody was generated by immunization of rabbits with pTH (1-34) coupled to a carrier protein.
Synonyms	parathormone; Parathyrin; PTH1
Reference Data

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